At birth, we have as many as 300 different bones in our body, but when we grow up we have 206 left. Make no mistake, we don’t lose them while growing up, only some of them merge and grow together.
Bones are made up of the protein collagen, which is fortified with minerals such as calcium, phosphorus and sodium. Although bones stop growing during puberty, we must be aware that bone density and thus their strength change throughout life. Therefore, it is important to provide the body with adequate nutrients to help maintain healthy bones.
Studies have shown that the addition of a dietary supplement rich in collagen peptides has a positive effect on bone mineral density (source 1). This problem is especially present in women entering menopause. During this time, there is a reduced production of estrogen, a hormone that is produced in the ovaries and affects the imbalance between bone breakdown and formation, so that the patient loses more bone than is being replaced. An imbalance that lasts for years can lead to osteoporosis.
Animal studies have shown that the addition of hyaluronic acid slows bone loss in rats with osteopenia, which is the initial stage of osteoporosis (sources 2 and 3). It has also been shown that high doses of hyaluronic acid can increase the activity of osteoblasts - the cells responsible for building new bone tissue (sources 4 and 5).
Is needed to maintain healthy bones.
Contributes to the normal absorption of calcium and to maintaining healthy bone.
- Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study Daniel König, Steffen Oesser, Stephan Scharla, Denise Zdzieblik, and Albert Gollhofer
- Stancíková M, Svík K, Istok R, Rovenský J, Velebný V. The effects of hyaluronan on bone resorption and bone mineral density in a rat model of estrogen deficiency-induced osteopenia. Int J Tissue React. 2004;26(1-2):9-16. PMID: 15573687
- Lajeunesse D, Delalandre A, Martel-Pelletier J, Pelletier JP. Hyaluronic acid reverses the abnormal synthetic activity of human osteoarthritic subchondral bone osteoblasts. Bone. 2003 Oct;33(4):703-10.DOI: 10.1016/s8756-3282(03)00206-0
- Huang L, Cheng YY, Koo PL, Lee KM, Qin L, Cheng JC, Kumta SM. The effect of hyaluronan on osteoblast proliferation and differentiation in rat calvarial-derived cell cultures. J Biomed Mater Res A. 2003 Sep 15;66(4):880-4. DOI:10.1002/jbm.a.10535